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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '304c646c71e26c73b9e2098a441314af75c786a8c66a08cf6a2f6c439e3d68df' 
  AND token = '6gmSIjsFhEg6N+LvMjgRBf4GgxWWlBvWwzkX9SgtnoA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}