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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42691aa89a6f23f6677d2178040411d4af5fc9b515f57964b126bc2fde8b6ba2' 
  AND token = 'Ei4DKUeRh26CbOdhq5FAyEcWhqVUB+chs2pOUHJV0ZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}