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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e7a71901c725d6865fbb1e9fd995124c96be8a93bdf7d1ef3a3f9820065106e' 
  AND token = 'Wj4GYUpcc55r1JhT9InzyLzobJXd/0zWIHbkP/TByc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}