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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7595e3997c3f7a9646c32d4e46b415d41290e6d8a220da8f1ddf2e0d9ac4d9fe' 
  AND token = 'e9dy5V714seik9K573Dnker5VD0PV8XKU6MA5zqa19c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}