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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7e42b260fbdf0386b425882de5b6cf13d1452760bbfd47a327d43101c7f8cb1' 
  AND token = 'bS8+qj/YY9NeYNA7qy0gznP9MtybkAAy5n3xKeDMoHw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}