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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5396a2d5140322911e00dfdabb8f47e250da952d61e67a5d458591748195f9f6' 
  AND token = 'mHMCRe1+L8H+np7bR3Ghq+Re+LZ/8gL6qfma2lPTGyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}