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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdd9c3fceaa2cf3ab234de0b4a9428bdcc52b9db9d3227f679685de39e9edae0' 
  AND token = 'ds23X63iKZkjc/aoW8oVgbX2V55EWZMjOtSpUiWX4kM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}