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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '292762076347be8d696275c5bbcc58682ecdd56773c73a8ceb863efde321d0eb' 
  AND token = 'BF2o0F51X1bPNKcpk7pcaiwAQET/0tZaHN4R8wVPsSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}