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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21d359bbdbe57e531758355be6b8f0996774a0ea18bf4158c3cd09a97ed25ebc' 
  AND token = 'Bhs1pTPMAUBc8tjX62RSn+saXJ5ogYQJ2GnGKrmTU+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}