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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c94f6f8bcd0eb472c1886d339d497c91af89f473842d3bf726e814ac648ea799' 
  AND token = '2lb4SZ6pov/FpiPZVsP6ncp4n3Wp5SlpDPE6zRVOjyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00076

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}