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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10cfd72326b1bb7b0c1b1ef64efda624f72ed0ed40cbea6936de2decea015590' 
  AND token = 'lV1Po+Xz26QgXinAD3967xAnanhXl0e+tf59aBqsC6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}