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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '287d60e07bf052db9809147d1a0fa0b075f585c3ff7dd32de64f93c0624dfb0e' 
  AND token = '1G/XJxotBh/jlc4WUCyPeEa3c0JI2u23YoySgaZQfU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}