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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd33d16f24249b69d6cc85a9244f4333fbaebe9a3d90fb15c0cfa106541c04197' 
  AND token = 'wU6c2eqmF5ALqGB7OL8NVM3Mrli2ogD2wWF1CVKVUvc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}