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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '346df194073feb91281056b5c151c417549a03347a8482b4feaf2239ee428c88' 
  AND token = '36HDH6M9sSAVkvaufrXuDocc/p0rHvNgxDhV2aOI1/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}