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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c33191868c2f34c3b2d9de2d3ead47c7457eece12cd45e0402443665a0bcf0cb' 
  AND token = 'P89hbwwTz+t8gzdhS/euc+fdtiXBFFSsurVOcp+/3Qc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}