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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f24a218d117b3d7beb06394706516390424aa254f7e66f4768a890b40a1abaa7' 
  AND token = 'i6UaeZv9q2Y7cp684rKMBVPjpt1EXZ+XxOrA3uCDokY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}