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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78c567ae50d4d106f1f554372e7dc25c5453bc6179d656d72d87f087268f4e9c' 
  AND token = 'uiDtEK98fpLBaX4l0/OgHF/JRsnTjMU/w7/CeS3scP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}