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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5bfc1c588bce7c1830d405df85a952df8a8214b1557cb00079157a89b562a2e' 
  AND token = 'kaqP+bqm2z57X5gQP76WmhmNMtB5wQum1XEiZ2E8WXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}