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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d8f6c66bbcb9429bb9443e6899eccc909d62e8279bedb7dcfd75d99ca84c2a8' 
  AND token = 'HHOPVxVqTxN4N9h4YDOaubwz6b5xlvNaImrX64IL1uU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}