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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2049ef3f8c9d6023b321543fc4b1f95783dfdc9af3320da932375a43d7eec5ff' 
  AND token = '44aNHps7rEH+5ywjLpjcaUFKYN6rm6Gtbr3eVuULrjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}