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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4781e5931d9416c6318256f81b206e4b30d76f53899850bc2f8b4c2afed018ce' 
  AND token = 'cFXnXuGd4S0RpWmxUxqGGXX6PdCeufgKqURKBNSqnUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}