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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ef509da6d4f50bd4a0b15f6bc089531f05b8de965a003d8a1ecfdc657716853' 
  AND token = 'fWPxIx0vcpf3xQ24l7kdjjRyMdlOATG9AIQbglnMNy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}