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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63f8ec20e398370621b2b50ef9b5c8a8d677c3ffdeff09c5a75686c910e88203' 
  AND token = 'Pln+jTk9CzQSJpHAoFQTxTCfyU1UASTM7YSbNr/IrPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}