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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6381fed58498164023f413450e744173a89e18abda4e70857f51cee5bc8a1271' 
  AND token = 'hTqx3/npMmuuILQe4X0Ze5/+p0H5+ZFTIZxpFnMulpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}