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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '123cc6ac13dc949fcb2f2314f33f93064914c3454b6b28f149f1b9a6b4d11597' 
  AND token = 'mA1vtK6TmWMfVhJNf+05CJVjE8BDVYDRcsPfBT9QyZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}