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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '781c8607a6041d38ff122e1dda6d952efc5d5888734e865bf0c2a161f08a1c9c' 
  AND token = 'NRa0P2y69t9LxsQoZYshOCUyUI3IK7ibsz3uM6Zif1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}