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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c45a045751b88327eab810df9a2b9c7a82f816a238e916725572f757865a6f8' 
  AND token = 'jkbIUa5agVT9gcQ8OAuRmqoS1Z5SybfKRID3+IiUEzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}