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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e22b3a71689f5267e7d4a47d87abe1bba18d58a1aff7c0c261a6971ad4979e7' 
  AND token = 'oBOy16JIB274qjlX/FxZFmCXVHvJMC64FOsSgm94VLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}