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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3f4163883b22b974682ab6c8f0485c2b9d90379c307e1e30a47b1bfe5e62818' 
  AND token = 'zn1a7Y9yX5Pfgq7tyWT1HYukZc7PFk+ES+kwk6eHKPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}