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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3fff96a07d33dc446af49983a9f8efa7f037443cb5af1c9739cb7e249c45f1a' 
  AND token = 'GxOKlploPolwyhKKI02vPcrHi0wfGF/dW1lynIMwrbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}