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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c90b1da3caa3665214cae16ee66bd3be767fac897d015484d1f4b2f8d815728b' 
  AND token = 'AP2Vh3nOyK7rvCsbIjC2EMGMMowHReUqVtEKJAqGVXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}