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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f18148136373b54d9426d37124110d7388472aff34c1a7eb6e630caba0a27065' 
  AND token = '2PlFGC5HBMddMUebQtAZ8G48YfZZC1lSLBzd//z2t8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}