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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b2850fe64494d27f8ca98283e891a3eb3578152129723bf2db8e60a20290431' 
  AND token = 'wfN+a3c7g2IBm/cpK8QcjUOWGxMLEkU6DNnr0Mk/m0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}