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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c9c4cba0022524762027b0d1b588fad86f6ba8b63df55770ad6d59a404161a1' 
  AND token = 'R55lEKWY+2uLO6s+e2+MrXyqrlS+4ZPNzQDe2rmOzGg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}