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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2863401dd2cdf511a6943dbd35d820bcdc41e32f97c6323cda206e61314b778' 
  AND token = 'rqK6afOcSXXP3/sygJNMZKpqdxHjyUdrCEqKK3lJmr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}