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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d1c899007c30ea30f177473e1f41c7981fa76bda7d05a7923e443a79bf54dd5' 
  AND token = 'rSe8RICDI0YtKEr712mHGWkGDZFa1BefEgy7fd5hzR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}