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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac645a24e3a6d06cb72ecc3d80eb7bb2fcc85e1bdeb90ec3993cdffb9a3fa825' 
  AND token = 'wDfGjoY84hcDiI1NZXPeQJr1XJ3RuDSjkgXWDk08uGo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}