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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48f01e4b2b0134386025fcafafed45a9a26643e18ec90855889d5701d475898b' 
  AND token = 'nyj9RlIi6QVJ5fj9rEVhQCPEufw8JVRQHGVDjKGVDes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}