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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd05db5bbb54fc987417ae673b9b43555f24baaffdb7d42f9c7ceaadc0a622354' 
  AND token = 't/NqxPI3F6bPw/wlunv3wQwLUfrqeaHBD6rNkQb0bPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}