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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e80311c0a88c740c6ce62371877b214950303afa1c8643fe37e37b133d8d1b2' 
  AND token = 'f8M2kRZ4Dj+8nW6gOCuzBYZ6KQSacYrzF819IJHth/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}