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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6191f42761803beda1c6dd28cf978bbb0d7263b37e4377823cb216dab16e77b6' 
  AND token = 'R15ZtoVR66IAxgVv+8zjbvQQSPC3ywPWiM5UV8DPMME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00112

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}