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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72218008386cefe4e7cbe52e96f827a4b8cb90dd38838f05606de95bcf1c27d7' 
  AND token = '9lhJouRhhn6YEhjZDBeVrjLWaJRI2lMQBb4ZXRBhr7U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}