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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'caa7aff6f64ca1afdce1337525900dd47f8722577f853151c3deab3e91a4a222' 
  AND token = 'uomBi1DSE+g8Ki8qX0tNabNkJw8fS35Gp/5hRTQNNrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}