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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fbe5364aefd6d6ed9fa031c550a7f575e389db196d4e84956bc70fd4bb344a41' 
  AND token = 'EkNhKVSiT1rs/TA1B3PBVE4wFF/TEuR5RgaZkFmiO9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}