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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec602866fb973c530218b717db4f7482686e3f4085c22405779f4cc915cc616b' 
  AND token = 'JfOZN9AmWADLbVlKoDDZot2OBzCPvXow5+DlOrzyr0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}