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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad552d68a7293da7cc95e16ff12a1964dbf032cdde046f3c15ca0b8d8a45c124' 
  AND token = '00AqfS9NGv9nSqyUR1jWo4E1IeeYSFy753mSpp+ZKXw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}