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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43879247cce0c98c31917743d9be6ec7aa5e2c51eb8ea7542dc3efe1175e5c40' 
  AND token = '5V0I/Q1nZav/20tbjuWtGLdraqygYt/Dpg82Z2FAs3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}