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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cef65a6e8afa0d458e2901a327b09a48a754e070a2cbc9846c5d5942959587a' 
  AND token = 'Hi7Pkzkmw9Y4tEEMqKBSI93rkQpWD+MTrMONay/o4kM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}