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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50f7aba4bf8a766915fb54e64decbbad89df6f67d5508281f4b9e5ee0a4c4fff' 
  AND token = 'tJHOXsVk+AvX7qM2gjOR2Xi3APg5zQqlO5cOKzOgoFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}