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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6a9f2671df89f12ed6e389724a4264df8569287b44024c03cf936d668e08e4c' 
  AND token = 'WkXJzdnkCBDcOJmYcmso1sD6N37efVTcWJWB/0sr8kA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}